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Institute for Neuroscience
Gemeinsame Einrichtung für Neurowissenschaften 

Our laboratory studies how nerve cells can be programmed and reprogrammed depending on neural activity and neurotrophic factors. In transgenic mouse models we investigate activity-dependent mechanisms of learning and memory that depend on plastic chromatin reorganization in the cell nucleus. Another focus is to generate neurons from stem cells. We are developing protocols to differentiate human induced pluripotent stem cells (IPSCs) into specific neuronal populations. Based on these protocols we have established molecular models of human neurological disease.