Publications in Journals, FWF Project 9685, Characterisation of GTP-cyclohydrolase I
Ernst R. Werner, Divison of Biological Chemistry, Biocenter, Medical University of Innsbruck
Differential regulation of inducible nitric oxide synthase production in bovine and caprine macrophages. Adler, H., Adler, B., Peveri, P., Werner, E. R., Wachter, H., Peterhans, E., Jungi, T. W. (1996) J.Inf.Dis. 173, 971-978
Characterization of heme-deficient neuronal NO synthase reveals a role for heme in subunit dimerization and binding of the amino acid substrate and tetrahydrobiopterin. Klatt, P., Pfeiffer, S., List, B. M., Lehner, D., Glatter, O., Bächinger, H. P., Werner, E. R., Schmidt, K., Mayer, B. (1996) . J.Biol.Chem. 271, 7336-7342
Overexpression of neuronal nitric oxide synthase in insect cells reveals requirement of heme for tetrahydrobiopterin binding. List, B. M., Klatt, P., Werner, E. R., Schmidt, K., Mayer, B. (1996) Biochem.J. 315, 57-63
Biosynthesis of nitric oxide: dependence on pteridine metabolism. Werner, E. R., Werner-Felmayer, G., Wachter, H., Mayer, B. (1996) Rev.Physiol Biochem.Pharmacol. 127, 97-135
Brain biopterin metabolism in chrinic experimental hepatic encephalopathy. Bergvist, P. B. F., Werner, E. R., Apelqvist, G., Bugge, M., Wachter, H., Bengtson, F. (1995) Metabol.Brain Dis. 10, 143-157
2,4-Diamino-6-hydroxypyrimidine, an inhibitor of tetrahydrobiopterin synthesis, downregulates the expression of iNOS protein and mRNA in primary murine macrophages. Bogdan, C., Werner, E. R., Stenger, S., Wachter, H., Röllinghoff, M., Werner-Felmayer, G. (1995) FEBS Lett. 363, 69-74
In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxide. Mayer, B., Werner, E. R. (1995) Naunyn - Schmiedebergs Arch.Pharmacol. 351, 453-463
Kinetics and mechanism of tetrahydrobiopterin-induced oxidation of nitric oxide. Mayer, B., Klatt, P., Werner, E. R., Schmidt, K. (1995) J.Biol.Chem. 270, 655-659
Nitric oxide formation as predictive parameter for acute graft- versus-host disease after human allogeneic bone marrow transplantation. Weiss, G., Schwaighofer, H., Herold, M., Nachbaur, D., Wachter, H., Niederwieser, D., Werner, E. R. (1995) Transplantation 60, 1239-1244
The pteridine binding site of brain nitric oxide synthase. Klatt, P., Schmid, M., Leopold, E., Schmidt, K., Werner, E. R., Mayer, B. (1994) J.Biol.Chem. 269, 13861-13866
Identification of imidazole as L-arginine-competitive inhibitor of porcine brain nitric oxide synthase. Mayer, B., Klatt, P., Werner, E. R., Schmidt, K. (1994) . FEBS Lett. 350, 199-202
Molecular mechanisms of inhibition of brain nitric oxide synthase by the antinociceptive drug 7-nitro-indazole. Mayer, B., Klatt, P., Werner, E. R., Schmidt, K. (1994) Neuropharmacology 33, 1253-1259
Pteridine biosynthesis and nitric oxide synthase in Physarum polycephalum. Werner-Felmayer, G., Golderer, G., Werner, E. R., Gröbner, P., Wachter, H. (1994) Biochem.J. 304, 105-111
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