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OENB Jubilaeumfonds Project 9918,
Ascorbic acid, tetrahydrobiopterin and inducible nitric oxide synthase in human cells,
Ernst R. Werner, Divison of Biological Chemistry , Biocenter, Medical University of Innsbruck

Project leader: 

>>Ernst R. Werner (e-mail: ernst.r.werner@i-med.ac.at;)
Division of Biological Chemistry, Biocenter
Innsbruck MedicalUniversity
Fritz-Pregl-Str.3/VI
A-6020 Innsbruck, Austria

Project Start:January 1, 2003, Project End: December 31, 2004

Publications:

{alpha}-Tocopherol and Endothelial Nitric Oxide Synthesis. Heller, R., Werner-Felmayer, G., Werner, E. R. (2004) Ann.N.Y.Acad.Sci. 1031, 74-85

Alpha-tocopherol amplifies phosphorylation of endothelial nitric oxide synthase at serine 1177 and its short chain derivative trolox stabilizes tetrahydrobiopterin. Heller, R., Hecker, M., Stahmann, N., Thiele, J. J., Werner-Felmayer, G., Werner, E. R. (2004) Free Rad.Biol.Med. 37, 620-631

Tetrahydrobiopterin and nitric oxide: Mechanistic and pharmacological aspects. Werner, E. R., Gorren, A. C. F., Heller, R., Werner-Felmayer, G., Mayer, B. (2003)  Exp.Biol.Med. 228, 1291-1302