Karl Maly, MD., Ph.D.
Selected Publications:
Haller T, Dietl P, Pfaller K, Frick M, Mair N, Paulmichl M, Hess MW, Fürst H, Maly K. Fusion pore expansion is a slow, discontinuous and Ca2+ - dependent process regulating secretion from alveolar type II cells. . J Cell Biol. 2001, in press.
Cronauer MV, Nessler-Menardi C, Klocker H, Maly K, Hobisch A, Bartsch G, Culig Z. Androgen receptor protein is down-regulated by basic fibroblast growth factor in prostate cancer cells.Br J Cancer. 2000 Jan;82(1):39-45.
Uberall F, Hellbert K, Kampfer S, Maly K, Villunger A, Spitaler M, Mwanjewe J, Baier-Bitterlich G, Baier G, Grunicke HH. Evidence that atypical protein kinase C-lambda and atypical protein kinase C-zeta participate in Ras-mediated reorganization of the F-actin cytoskeleton. J Cell Biol. 1999 Feb 8;144(3):413-25.
Villunger A, Egle A, Kos M, Egle D, Tinhofer I, Henn T, Uberall F, Maly K, Greil R.
Functional granulocyte/macrophage colony stimulating factor receptor is constitutively expressed on neoplastic plasma cells and mediates tumour cell longevity. Br J Haematol. 1998 Sep;102(4):1069-80.
Zwick E, Daub H, Aoki N, Yamaguchi-Aoki Y, Tinhofer I, Maly K, Ullrich A. Critical role of calcium- dependent epidermal growth factor receptor transactivation in PC12 cell membrane depolarization and bradykinin signaling. J Biol Chem. 1997 Oct 3;272(40):24767-70.
Tinhofer I, Maly K, Dietl P, Hochholdinger F, Mayr S, Obermeier A, Grunicke HH.
Differential Ca2+ signaling induced by activation of the epidermal growth factor and nerve growth factor receptors. J Biol Chem. 1996 Nov 29;271(48):30505-9.
of mitogenic signal transduction. Adv Enzyme Regul. 1996;36:385-407.
Maly K, Kindler E, Tinhofer I, Grunicke HH.
Activation of Ca2+ influx by transforming Ha-ras. Cell Calcium. 1995 Aug;18(2):120-34.
Maly K, Uberall F, Schubert C, Kindler E, Stekar J, Brachwitz H, Grunicke HH.
Interference of new alkylphospholipid analogues with mitogenic signal transduction.
Anticancer Drug Des. 1995 Jul;10(5):411-25.
Meyer M, Maly K, Uberall F, Hoflacher J, Grunicke H.
Stimulation of K+ transport systems by Ha-ras. J Biol Chem. 1991 May 5;266(13):8230-5.
Lang F, Friedrich F, Kahn E, Woll E, Hammerer M, Waldegger S, Maly K, Grunicke H.
Bradykinin-induced oscillations of cell membrane potential in cells expressing the Ha-ras oncogene. J Biol Chem. 1991 Mar 15;266(8):4938-42.
Maly K, Uberall F, Loferer H, Doppler W, Oberhuber H, Groner B, Grunicke HH.
Ha-ras activates the Na+/H+ antiporter by a protein kinase C-independent mechanism.
J Biol Chem. 1989 Jul 15;264(20):11839-42.
Maly K, Doppler W, Oberhuber H, Meusburger H, Hofmann J, Jaggi R, Grunicke HH.
Desensitization of the Ca2+-mobilizing system to serum growth factors by Ha-ras and v-mos. Mol Cell Biol. 1988 Oct;8(10):4212-6.