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Clara Baldin, PhD

Clara_BaldinEMail: clara.baldin@i-med.ac.at

Phone: +43/(0)512/9003-70334

Fax: +43/(0)512-9003-73100

 

Short curriculum

2003-2006 Bachelor studies in Biotechnology, Univ. of Padua, Italy
2006-2009

Master studies in Industrial Biotechnology, Genomics and Functional Proteomics, Univ. of Padua, Italy

2010-2015 Doctoral studies in Microbiology, Department of Molecular and Applied Microbiology, Friedrich-Schiller University, Leibniz-Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute, Jena, Germany
2015-2017 Postdoctoral fellow, Department of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Los Angeles, CA , USA

2018-2019 Postdoctoral fellow, Institute of Molecular Biology, Med. Uni. Innsbruck, Austria
since 2019

University Assistant, Institute of Biological Chemistry, Med. Uni. Innsbruck, Austria 

since 2020

Principal Investigator, Institute of Molecular Biology, Med. Uni. Innsbruck, Austria

 

Awards

2010 - Marie Slodowska-Curie PhD fellowship: PhD international funding program

2017 - MBL Advanced Research Training Course Scholarship: Molecular Mycology course

2019 - FWF M 2867 Lise Meitner program, incoming scientist

MUI MyPoint - Meitner Project link
https://www.i-med.ac.at/mypoint/thema/744655.html

 

Research fields

Human pathogenic fungi

Structural and functional biology

 

Publications

  1. Soliman S.*, Baldin C.*, Gu Y.*, Singh S.*, Gebremariam T, Swidergall M., Alqarihi A., Youssef E., Alkhazragi S., Pikoulas A., Perske C., Venkataramani V., Rich A., Bruno V., Dunning Hotopp J., Mantis N., Edwards J. Jr., Filler S., Chamilos G., Vitetta E., Ibrahim A. (2020) “Mucoricin is a Ricin-Like Toxin that is Critical for the Pathogenesis of Mucormycosis.” Nat Microbiol. 2021 Jan 18. doi: 10.1038/s41564-020-00837-0
  2. Baldin C., Soliman S., Jeon H., Alkhazraji S., Gebremariam T., Bruno V., Cornely O., Sugrue M., Wingard J., Stevens D., Edwards J. Jr., Ibrahim A. (2018) "PCR-based approach targeting Mucorales specific gene family for the diagnosis of mucormycosis." J Clin Microbiol. 2018 Sep 25;56(10). pii: e00746-18
  3. Andrianaki A., Kyrmizi I., Panopoulou K., Baldin C., Drakos E., Soliman S. M., Akoumianaki T., Stylianou K., Ioannou P., Belle V., Emilien E., Beauvais A., Samonis G., Kontoyiannis D. P., Andreakos E., Bruno V., Ibrahim A. S., Chamilos G. (2018) “Iron restriction inside macrophages is an essential host defense mechanism against Mucorales” Nat Commun. 2018 Aug 20;9(1):3333
  4. Baldin C. and Ibrahim A. S. (2017) "Molecular Mechanisms of Mucormycosis – The Bitter and The Sweet." PLoS Pathog. 2017 Aug 3;13(8):e1006408. doi: 10.1371/journal.ppat.1006408. eCollection 2017 Aug.
  5. Gebremariam T., Alkhazraji S., Baldin C., Kovanda L., Wiederhold N.P., Ibrahim A.S. (2017). "Prophylaxis with Isavuconazole or Posaconazole Protect Immunosuppressed Mice from Pulmonary Mucormycosis." Antimicrob Agents Chemother. 2017 Mar 6. pii:AAC.02589-16
  6. Valiante V*, Baldin C.*, Hortschansky P., Jain R., Thywißen A., Straßburger M., Shelest E., Heinekamp T., Brakhage A. A. (2016). "The Aspergillus fumigatus conidial melanin production is regulated by the bifunctional bHLH DevR and MADS-box RlmA transcription factors." Mol Microbiol. Oct;102(2):321-335
  7. Altwasser R., Baldin C., Weber J., Guthke R., Kniemeyer O., Brakhage A.A., Linde J., Valiante V. (2015). "Network Modeling Reveals Cross Talk of MAP Kinases during Adaptation to Caspofungin Stress in Aspergillus fumigatus." PLoS One Sep 10;10(9):e0136932
  8. Baldin C., Valiante V., Krüger T., Schafferer L., Haas H., Kniemeyer O., Brakhage A. A. (2014). "Comparative proteomics of a tor inducible Aspergillus fumigatus mutant reveals involvement of the Tor kinase in iron regulation." Proteomics. 2015 Feb 27. doi: 10.1002/pmic.201400584
  9. Perez-Nadales, E., Nogueira M. F., Baldin C., Castanheira S., El Ghalid M., Grund E., Lengeler K., Marchegiani E., Mehrotra P. V., Moretti M., Naik V., Oses-Ruiz M., Oskarsson T., Schäfer K., Wasserstrom L., Brakhage A. A., Gow N. A., Kahmann R., Lebrun M. H., Perez-Martin J., Di Pietro A., Talbot N. J., Toquin V., Walther A., Wendland J. (2014). "Fungal model systems and the elucidation of pathogenicity determinants." Fungal Genet Biol 70: 42-67
  10. Müller, S., Baldin C., Groth M., Guthke R., Kniemeyer O., Brakhage A. A., Valiante V. (2012). "Comparison of transcriptome technologies in the pathogenic fungus Aspergillus fumigatus reveals novel insights into the genome and MpkA dependent gene expression." BMC Genomics 13: 519.

Institut für Molekularbiologie