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Selected Publications

SATB2 organizes the 3D genome architecture of cognition in cortical neurons

Nico Wahl, Sergio Espeso-Gil, Paola Chietera,  Amelie Nagel, Aodán Laighneach, Derek W. Morris, Prashanth Rajarajan, Schahram Akbarian, *Georg Dechant and *Galina Apostolova

Wahl et al., SATB2 organizes the 3D genome architecture of cognition in cortical neurons, Molecular Cell (2024), https://doi.org/10.1016/j.molcel.2023.12.024 

SATB2 organizes the 3D genome architecture of cognition in cortical neurons

iDNico Wahl, iDSergio Espeso-Gil, Paola Chietera, Aodán Laighneach, iDDerek W. Morris, iDPrashanth Rajarajan, iDSchahram Akbarian, iD*Georg Dechant, 
iD*Galina Apostolova

bioRxiv;2022.12.27.522010. doi: https://doi.org/10.1101/2022.12.27.522010

Chromatin Reorganization during Myoblast Differentiation Involves the Caspase-Dependent Removal of SATB2

Ryan A V Bell ^1 2, Mohammad H Al-Khalaf ^1 2 3, Steve Brunette ¹, Dalal Alsowaida ^1 2, Alphonse Chu ^1 2, Hina Bandukwala ¹, Georg Dechant ⁴, Galina Apostolova ⁴, F Jeffrey Dilworth ^1 2, Lynn A Megeney ^1 2

Cells 2022, 11, 966. https://doi.org/10.3390/cells11060966

Cell-type specialization is encoded by specific chromatin topologies

Warren Winick-Ng1,22 ✉, Alexander Kukalev1,22, Izabela Harabula1,2,22, Luna Zea-Redondo1,2,22, Dominik Szabó1,2,22, Mandy Meijer3, Leonid Serebreni1,16, Yingnan Zhang4, Simona Bianco5, Andrea M. Chiariello5, Ibai Irastorza-Azcarate1, Christoph J. Thieme1, Thomas M. Sparks1, Sílvia Carvalho1,6,7,8, Luca Fiorillo5, Francesco Musella5, Ehsan Irani1,9, Elena Torlai Triglia1,17, Aleksandra A. Kolodziejczyk10,11,18, Andreas Abentung12,19, Galina Apostolova12, Eleanor J. Paul13,20,21, Vedran Franke14, Rieke Kempfer1,2, Altuna Akalin14, Sarah A. Teichmann10,11, Georg Dechant12, Mark A. Ungless13, Mario Nicodemi5,9, Lonnie Welch4, Gonçalo Castelo-Branco3,15 & Ana Pombo1,2,9 ✉

Nature 599, 684–691 (2021). https://doi.org/10.1038/s41586-021-04081-2

SATB2-LEMD2 interaction link nuclear shape plasticity to regulation of cognition-related genes

Patrick Feurle^1*, Andreas Abentung^1*, Isabella Cera^1*, Nico Wahl^1*, Cornelia Ablinger¹, Michael Bucher², Eduard Stefan², Simon Sprenger³, David Teis³, Andre Fischer^4,5, Aodán Laighneach⁶, Laura Whitton⁶, Derek W. Morris⁶, Galina Apostolova^1# and Georg Dechant^1#

The EMBO journal 40 (3), e103701. DOI: 10.15252/embj.2019103701.

Genes encoding SATB2-interacting proteins in adult cerebral cortex contribute to human cognitive ability.

Cera I, Whitton L, Donohoe G, Morris DW, Dechant G, Apostolova G.

PLoS Genet. 2019 Feb 6;15(2):e1007890. doi: 10.1371/journal.pgen.1007890. eCollection 2019 Feb.

Cocaine Paired Environment Increases SATB2 Levels in the Rat Paraventricular Thalamus.

Salti A, Apostolova G, Kummer KK, Lemos C, Dechant G, El Rawas R.

Front Behav Neurosci. 2018 Oct 2;12:224. doi: 10.3389/fnbeh.2018.00224. eCollection 2018.

Genes regulated by SATB2 during neurodevelopment contribute to schizophrenia and educational attainment.

Whitton L, Apostolova G, Rieder D, Dechant G, Rea S, Donohoe G, Morris DW.

PLoS Genet. 2018 Jul 24;14(7):e1007515. doi: 10.1371/journal.pgen.1007515. eCollection 2018 Jul.

Bicistronic CACNA1A Gene Expression in Neurons Derived from Spinocerebellar Ataxia Type 6 Patient-Induced Pluripotent Stem Cells.

Bavassano C, Eigentler A, Stanika R, Obermair GJ, Boesch S, Dechant G, Nat R.

Stem Cells Dev. 2017 Nov 15;26(22):1612-1625. doi: 10.1089/scd.2017.0085. Epub 2017 Oct  

Satb2 determines miRNA expression and long-term memory in the adult central nervous system.

Jaitner C, Reddy C, Abentung A, Whittle N, Rieder D, Delekate A, Korte M, Jain G, Fischer A, Sananbenesi F, Cera I, Singewald N, Dechant G, Apostolova G.

Elife. 2016 Nov 29;5. pii: e17361. doi: 10.7554/eLife.17361