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Hubertus Haas Ph.D., Professor

hubertus_haasEMail: hubertus.haas[at]i-med.ac.at

Phone: +43/(0)512/9003-70205

Fax: +43/(0)512-9003-73100

 

Short curriculum

1983-1988 Studies of Microbiology at the University of Innsbruck/Austria 
1988  Master degree (Mag.rer.nat.), Master thesis: "Establishment of a phleomycin resistance based
transformation system for Penicillium chrysogenum" at the Biochemie GmbH Kundl (Novartis) / Austria
1990  EMBO-Short-Term-Fellowship at the "Max-Planck-Institut für Molekulare Genetik" in Berlin/Germany 
1991  Ph.D. degree (Dr. rer. nat.), Ph.D. thesis: "Characterization of extracellular enzymes and the
encoding genes of Penicillium chrysogenum" at the Department of Microbiology (Med. School)/
University of Innsbruck and at the Biochemie GmbH Kundl(Novartis) / Austria
since 1993 Assistant professor at the Department of Molecular Biology at the University of Innsbruck 
1993-1994 Schrödinger Long-Term-Fellowship at the Department of Biochemistry, Columbus, Ohio/USA 
1999 "Habilitation" (venia docendi) in Microbiology
1999-2019 Associate professor at the Department of Molecular Biology at the University of Innsbruck
since 2019 Professor at the Department of Molecular Biology  at the University of Innsbruck

 

Awards

1996 - Höchst Award

1998 - Brandl Award

 

Research fields

Molecular Microbiology

 

Teaching

From the online catalog of the Innsbruck Medical University (in German): Current lectures

From the online catalog of the University of Innsbruck (in German): Current lectures

 

Publications

please see:
PubMed

Publications not listed in this link:

  1. Gaspar-Cordeiro A, da Silva S, Aguiar M, Haas H, Lima LMP, Pimentel C (2020). A copper(II)-binding triazole derivative with ionophore properties is active against Candida spp. J. Biol. Inorg. Chem. 25:1117-1128.
  2. Lackner M, Coassin S, Haun M, Binder U, Kronenberg F, Haas H, Jank M, Meis JF, Hage F, Lass-Flörl C (2016). Geographically predominant genotypes of Aspergillus terreus species complex in Austria: a microsatellite typing study. Clin. Microbiol. Infect. 22:270-6.
  3. Seifert M, Nairz M, Schroll A, Schrettl M, Haas H & Weiss G (2008). Effects of the Aspergillus fumigatus siderophore systems on the regulation of macrophage immune effector pathways and iron homeostasis. Immunobiology 213:767-778. 
  4. Leiter, E., Marx, F., Pusztahelyi, T., Haas, H. and Pocsi, I. (2004) Penicillium chrysogenum glucose oxidase - a study on its antifungal effects. J. Appl. Microbiol. 97: 1201-1209. 
  5. Haas H (2003). Molecular genetics of fungal siderophore biosynthesis and uptake: the role of siderophores in iron uptake and storage.  Microbiol. Biot.62: 316-30. 
  6. Oberegger H, Zadra I, Schoeser M, Abt B, Parson W & Haas H (2002). Identification of members of the Aspergillus nidulansSREA regulon: genes involved in siderophore biosynthesis and utilization.  Soc. Trans. 30(4):781-783  
  7. Oberegger H, Schoeser M, Zadra I, Abt B & Haas H (2001). SREA is involved in regulation of siderophore biosynthesis, utilization and uptake in Aspergillus nidulans. Microbiol.41(5): 1077-1089.  
  8. Conlon H, Zadra I, Haas H, Arst HN, Jones MG & Caddick MX (2001). The Aspergillus nidulansGATA transcription factor gene areBencodes at least three proteins and features three classes of mutation.  Microbiol. 40(2): 361-375.  
  9. Dangl M, Brosch G, Haas H, Loidl P & Lusser A (2001). Comparative analysis of HD2 type histone deacetylases in higher plants. Planta 213,280-285.  
  10. Oberegger H, Zadra I, Schoeser M & Haas H (2000). Iron starvation leads to increased expression of Cu/Zn-superoxide dismutase in  FEBS letters, 485:113-116.  
  11. Zadra I, Abt B, Parson W & Haas H (2000). AxylP promoter-based expression system and its use for antisense downregulation of the Penicillium chrysogenumnitrogen regulator NRE.  Environ. Microbiol. 66:4810-4816.  
  12. Feng B, Haas H & Marzluf GA (2000). ASD4, a new GATA factor of Neurospora crassa,displays sequence-specific DNA binding and functions in ascus and ascospore development. Biochemistry 39:11065-73.  
  13. Graessle S, Dangl M, Haas H, Mair K, Trojer P, Brandtner E, Walton JD, Loidl P & Brosch G. (2000). Characterization of two putative histone deacylase genes from Aspergillus nidulans. Biophys. Acta1492:120-6.  
  14. Lusser A, Eberharter A, Loidl A, Goralik-Schramel M, Haas H & Loidl P (1999). Analysis of the histone acetyltransferasae B complex of maize embryos.  Acids Res.27:4427-35.  
  15. Haas H (1999). GATA- factors and nitrogen metabolism in filamentous fungi. Amino Acids 17:98. Abstract.  
  16. Haas H, Zadra I, Stöffler G & Angermayr K (1999). The Aspergillus nidulansGATA-factor SREA is involved in regulation of siderophore biosynthesis and control of iron uptake.  Biol. Chem. 274:4613-4619.  
  17. Angermayr K, Parson W, Stöffler G & Haas H (1999). Expression of atrC- encoding a novel member of the ATP-binding cassette transporter family in Aspergillus nidulans - is sensitive to cycloheximide.  Biophys. Acta 1453:304-310.  
  18. Dangl M, Lusser A, Brosch G, Loidl A, Haas H & Loidl P (1998). Second family of histone deacetylases. Science280:1167a (www.sciencemag.org). Technical comment.  
  19. Zhou L, Haas H & Marzluf GA (1998). Isolation and characterization of a new gene, sre, which encodes a GATA-type regulatory protein that controls iron transport in Neurospora crassa. Gen. Genet.259:532-540.  
  20. Haas H, Angermayr K, Zadra I, & Stöffler G (1997). Overexpression ofnreB, a new GATA factor-encoding gene of Penicillium chrysogenum, leads to repression of the nitrate assimilatory gene cluster.  Biol. Chem. 272:22576-22582.  
  21. Lusser A, Brosch G, Loidl A, Haas H & Loidl P (1997). Identification of maize histone deacetylase HD2 as an acidic nucleolar phosphoprotein. Science277:88-91.  
  22. Lusser A, Brosch G, Loidl A, Haas H & Loidl P (1997). A Novel Type of Histonedeacetylases: Molecular Cloning and Sequencing of HD2 of  mays. 17th International Congress of Biochemistry and Molecular Biology, FASEB Journal11(9). Abstract.  
  23. Graessle S, Haas H, Friedlin E, Kürnsteiner H, Stöffler G & Redl B (1997). Regulated system for heterologous gene expression in Penicllium chrysogenum. Appl. Env. 63:753-756.  
  24. Haas H, Angermayr K & Stöffler G (1997). Molecular analysis of a Penicillium chrysogenumGATA factor encoding gene (sreP) exhibiting significant homology to the Ustilago maydis urbs1 Gene 184:33-37.  
  25. Haas H, Zadra I & Graessle S (1996). Partial sequence of the actin encoding gene (actA) of Penicillium chrysogenum. GenBank accession number U61733.  
  26. Haas H, Marx F, Graessle S & Stöffler G (1996). Sequence analysis and expression of the Penicillium chrysogenumnitrate reductase encoding gene (niaD). Biophys. Acta 1309:81-84.  
  27. Marx F, Haas H, Reindl M, Stöffler G, Lottspeich F & Redl B (1995). Cloning, structural organization and regulation of expression of the Penicillium chrysogenumpaf gene encoding an abundantly secreted protein with antifungal activity. Gene 167:167-171.  
  28. Marx F, Haas H, Hofer S, Stöffler G & Redl B (1995). Sequence and structure of Penicillium chrysogenum phoG, homologous to an acid phosphatase encoding gene of Aspergillus nidulansGene160:137-138.  
  29. Haas H & Marzluf GA (1995). NRE, the major nitrogen regulatory protein of Penicillium chrysogenum, binds specifically in the intergenic promoter regions of nitrate assimilation and penicillin biosynthetic gene clusters.  Genet.28:177-183.  
  30. Haas H, Bauer B, Redl B, Stöffler G & Marzluf GA (1995). Molecular cloning and analysis of nre, the major nitrogen regulatory gene of Penicillium chrysogenum Genet.27:150-158.  
  31. Haas H, Friedlin E, Stöffler G & Redl B (1993). Cloning and structural organization of a xylanase-encoding gene from Penicillium chrysogenumGene126:237-242.  
  32. Haas H, Redl B, Herfurth E & Stöffler G (1992). Purification, characterization and partial amino acid sequences of a xylanase produced by Penicillium chrysogenum. Biophys. Acta1117:279-286.  
  33. Haas H, Redl B, Friedlin E & Stöffler G (1992). Isolation and molecular analysis of the Penicillium chrysogenumphoA gene encoding a secreted phosphate-repressible acid phosphatase. Gene 113:129-133.  
  34. Haas H, Redl B, Leitner E & Stöffler G (1991). Penicillium chrysogenumextracellular acid phosphatase: purification and biochemical characterization. Biophys. Acta 1074:392-397. 

Institut für Molekularbiologie